SciClix is focused on the discovery, design, and development of compounds made from novel building-blocks. Novel building-blocks allow for exploration of new chemical space and hold a tremendous potential for new discoveries in various chemical industries such as pharmaceutical, agrochemistry, polymer, food and fragrances etc.
Resveratrol Resveratrol is a natural polyphenol that has an array of biological activities but poor pharmacokinetic properties. Maximum concentration achieved in vivo is 273 ng/ml.
Tyrosine Tyrosine is a common amino acid that is extensively used in peptide synthesis.
BCP- resveratrol Bioisosteric modification of Resveratrol to BCP- resveratrol improves the pharmacokinetic properties. Maximum concentration achieved in vivo is 942 ng/ml.
BCP-tyrosine This will be an intriguing building block with potential uses in peptides and other functional molecules
ACS Med. Chem. Lett., 2017, 8 (5), pp 516–520. Towards Resolving the Resveratrol Conundrum: Synthesis and in Vivo Pharmacokinetic Evaluation of BCP–Resveratrol
Our Business DNA
We make, use, sell and advocate new building-blocks. Novel motifs are in the DNA of everything we do.
We are continuously exploring and developing new applications of non-traditional building-blocks. The focus of our discovery endeavor is to introduce more efficient functional molecules in chemicals-related field such as pharmaceuticals, agrochemistry, fragrances etc. Our mission will exemplify the utility of novel building blocks and propel them to mainstream discovery projects. In short, SciClix is working towards making novel motifs click!
Synthesizing useful functional molecules with novel building-blocks may lead to faster overall development time and high success rates. The fundamental science behind the effective use of novel building-blocks however is not exactly trivial and needs thorough exploration. The good news is that we have already been working towards gaining such insights and have secured good understanding of the behavior of our building-blocks. With our experience in this area, we may be able to help you expedite your discovery efforts. Join forces with SciClix, and we will make your science click!
Over the years, we have synthesized several novel and useful building-blocks. And we will continue to do so. Take a look at our building-block collection and let us know if anything interests you or anything that you may like us forge for you. We are happy to share and we are happy to help! Afterall, science clicks the best when it’s a shared zest.
If you have great ideas but no experience in synthesis experience and no testing facilities. Worry not. Talk to us, we are churning molecules all the time, and we will be happy to spare some effort for you. Not just that, we may also help you test your molecules. To put it simply, whenever you are in a synthetic fix, think of SciClix!
Lay a strong foundation to your discovery endeavour by using the right building-blocks. Afterall, it is the fabric of your molecule that decides its success.
Working in silo is not our thing. If you want to discuss some science, get in-touch.